Processive Catalysts

Recently, in our group, a considerable amount of research has been directed toward the area of catalytic rotaxanes. A mono-cavity manganese porphyrin has been shown to be catalytically active in the epoxidation of olefins via a pseudo-rotaxane mechanism. The synthesis of rotaxanes via a novel olefin metathesis route using the mono-cavity H2-porphyrin also has been reported. Furthermore, a related double-cavity porphyrin has been synthesised, for which a highly negative homotropic allosteric binding of viologens has been observed.

Subprojects:

Onno I. van den Boomen Onno I. van den Boomen Phone: 52022	The construction of a processive catalyst; a DNA-polymerase mimic
Cyrille Monnereau Cyrille Monnereau Phone: 52028	Study on the catalytic properties of various porphyrin clips
Alexander B.C. Deutman Alexander B.C. Deutman Phone: 52028	no title yet
Pilar Hidalgo Ramos Pilar Hidalgo Ramos Phone: 52028	no title yet

• P. Hidalgo Ramos, R. Coumans, A. B. C. Deutman, R. de Gelder, J. M. M. Smits, J. A. A. W. Elemans, R. J. M. Nolte, A. E. Rowan, Processive rotaxane catalysts. Studies on the mechanism of the threading process, J. Am. Chem. Soc., 129, 17, 5699-5702 (2007).
  PDF doi:10.1021/ja068714i
  
  
• P.J. Thomassen, J. Foekema, R. Jordana i Lluch, P. Thordarson, J.A.A.W. Elemans, R.J.M. Nolte, A.E. Rowan, Self-assembly studies of allosteric photosynthetic antenna model systems, New J. Chem., 30, 2, 148-155 (2006).
  PDF doi:10.1039/b510968j
  
  
• P.J. Thomassen, N. Veling, J.A.A.W. Elemans, R.J.M. Nolte and A.E. Rowan, Allosterically driven multicomponent assembly as a tool to construct supramolecular polymers, Polymer Preprints, 47, 148-155 (2006).